Damaged AECs release pro-inflammatory and pro-fibrotic mediators, including interleukin (IL) -1 and tumor necrosis factor (TNF) -, which promote fibroblast recruitment, inflammatory cell activation (e.g., neutrophils, Th17, gdT cells), and myofibroblast differentiation, ultimately leading to ECM accumulation and fibrotic tissue remodeling [20, 29, 33, 34]
A single vigorous shake can create billions of tiny bubbles, each one a site of potential peptide damage
Research applications include multi-tissue regeneration, multi-site injuries, inflammatory control, and functional recovery in musculoskeletal and soft-tissue systems
First Line Polyethylene glycol (Miralax) 17 grams daily in water Safe and effective Takes 23 days Magnesium citrate (powder) Adjustable dose Helps draw water into stool Add If Needed Fiber supplements Psyllium (Metamucil), methylcellulose Start low, go slow Stool softeners Docusate Helpful if straining Rescue (Not Daily) Stimulants Senna or bisacodyl Use as needed, not every day When to Call Your Doctor Call right away if you have: No bowel movement for more than 57 days Severe abdominal pain Vomiting Blood in stool or black stools Severe bloating One More Thing Before We Get Practical I start my day with a breakfast shake
:max_bytes(150000):strip_icc()/VWH-MiraNorian-WeightLossDrugUpdate-4000x2700-c813fa5051604eec9c136047fb44d23a.png)
